| ncRNA Symbol: | LDOC1 |
| Full Name: | LDOC1, regulator of NFKB signaling |
| Category: | mRNA |
| Synonyms: | BCUR1|Mar7|Mart7|RTL7|SIRH7 |
| Chromosome: | chrX |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 141175745 | End Site(bp): | 141177125 | |
| Gene Summary: | The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008] |
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