ctcRbase

Entry Detail

---



General Information

Database ID: BRCA11650 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: MICU1 Full Name: mitochondrial calcium uptake 1 Category: mRNA Synonyms: CALC|CBARA1|EFHA3|MPXPS|ara CALC Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 72367327 End Site(bp): 72626191 Gene Summary: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013] External Links: Ensembl ID: ENSG00000107745 HGNC ID: HGNC:1530 Entrez Gene: 10367

Expression Profile of MICU1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-137 YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES NO NO hsa-miR-183-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-424-5p YES NO NO hsa-miR-485-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-613 YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-9-5p YES YES NO Display: