ctcRbase

Entry Detail

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General Information

Database ID: BRCA12002 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HIST2H2BE Full Name: histone cluster 2 H2B family member e Category: mRNA Synonyms: GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 149884459 End Site(bp): 149886652 Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity. [provided by RefSeq, Aug 2015] External Links: Ensembl ID: ENSG00000184678 HGNC ID: HGNC:4760 Entrez Gene: 8349

Expression Profile of HIST2H2BE Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-154-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-760 YES NO YES Display: