ctcRbase

Entry Detail

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General Information

Database ID: BRCA12071 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: AKAP8 Full Name: A-kinase anchoring protein 8 Category: mRNA Synonyms: AKAP 95|AKAP-8|AKAP-95|AKAP95 Chromosome: chr19 Strand: - Coordinate: Start Site(bp): 15353385 End Site(bp): 15379798 Gene Summary: This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011] External Links: Ensembl ID: ENSG00000105127 HGNC ID: HGNC:378 Entrez Gene: 10270

Expression Profile of AKAP8 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-98-5p YES YES NO Display: