ctcRbase

Entry Detail

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General Information

Database ID: BRCA12135 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: MYOF Full Name: myoferlin Category: mRNA Synonyms: FER1L3 Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 93306429 End Site(bp): 93482317 Gene Summary: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined. [provided by RefSeq, Dec 2008] External Links: Ensembl ID: ENSG00000138119 HGNC ID: HGNC:3656 Entrez Gene: 26509

Expression Profile of MYOF Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-154-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-543 YES YES NO Display: