ctcRbase

Entry Detail

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General Information

Database ID: BRCA12208 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: HNF4A Full Name: hepatocyte nuclear factor 4 alpha Category: mRNA Synonyms: FRTS4|HNF4|HNF4a7|HNF4a8|HNF4a9|HNF4alpha|MODY|MODY1|NR2A1|NR2A21|TCF|TCF14 Chromosome: chr20 Strand: + Coordinate: Start Site(bp): 44355700 End Site(bp): 44434596 Gene Summary: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012] External Links: Ensembl ID: ENSG00000101076 HGNC ID: HGNC:5024 Entrez Gene: 3172

Expression Profile of HNF4A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-214-3p YES NO NO hsa-miR-216b-5p YES YES NO hsa-miR-326 YES YES YES hsa-miR-328-3p YES YES NO hsa-miR-330-5p YES YES YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-485-5p YES YES YES Display: