ctcRbase

Entry Detail

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General Information

Database ID: BRCA13691 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: DBT Full Name: dihydrolipoamide branched chain transacylase E2 Category: mRNA Synonyms: BCATE2|BCKAD-E2|BCKADE2|BCOADC-E2|E2|E2B Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 100186919 End Site(bp): 100249834 Gene Summary: The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000137992 HGNC ID: HGNC:2698 Entrez Gene: 1629

Expression Profile of DBT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-192-5p YES NO YES hsa-miR-215-5p YES NO YES hsa-miR-25-3p YES NO YES hsa-miR-32-5p YES NO YES hsa-miR-363-3p YES NO YES hsa-miR-367-3p YES NO YES hsa-miR-542-3p YES NO YES hsa-miR-92a-3p YES NO YES hsa-miR-92b-3p YES NO YES Display: