ctcRbase

Entry Detail

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General Information

Database ID: BRCA13812 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: HNF1B Full Name: HNF1 homeobox B Category: mRNA Synonyms: FJHN|HNF-1-beta|HNF-1B|HNF1beta|HNF2|HPC11|LF-B3|LFB3|MODY5|TCF-2|TCF2|VHNF1 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 37686432 End Site(bp): 37745247 Gene Summary: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] External Links: Ensembl ID: ENSG00000275410 HGNC ID: HGNC:11630 Entrez Gene: 6928

Expression Profile of HNF1B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-219a-5p YES YES NO hsa-miR-24-3p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-299-3p YES YES NO hsa-miR-32-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-874-3p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: