ctcRbase

Entry Detail

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General Information

Database ID: BRCA13988 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: DGCR2 Full Name: DiGeorge syndrome critical region gene 2 Category: mRNA Synonyms: DGS-C|IDD|LAN|SEZ-12 Chromosome: chr22 Strand: - Coordinate: Start Site(bp): 19036282 End Site(bp): 19122454 Gene Summary: Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] External Links: Ensembl ID: ENSG00000070413 HGNC ID: HGNC:2845 Entrez Gene: 9993

Expression Profile of DGCR2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES NO YES hsa-miR-1271-5p YES NO YES hsa-miR-128-3p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES NO YES hsa-miR-183-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-342-3p YES NO YES hsa-miR-96-5p YES NO YES Display: