ctcRbase

Entry Detail

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General Information

Database ID: BRCA14083 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: KLF5 Full Name: Kruppel like factor 5 Category: mRNA Synonyms: BTEB2|CKLF|IKLF Chromosome: chr13 Strand: + Coordinate: Start Site(bp): 73054976 End Site(bp): 73077542 Gene Summary: This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] External Links: Ensembl ID: ENSG00000102554 HGNC ID: HGNC:6349 Entrez Gene: 688

Expression Profile of KLF5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-124-3p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-136-5p YES YES NO hsa-miR-137 YES YES NO hsa-miR-140-3p YES NO YES hsa-miR-141-3p YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-145-5p YES YES YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-153-3p YES YES YES hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-21-5p YES YES YES hsa-miR-217 YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-32-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-375 YES NO YES hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-448 YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-499a-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-590-5p YES YES YES hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-9-5p YES YES YES hsa-miR-96-5p YES YES NO Display: