ctcRbase

Entry Detail

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General Information

Database ID: BRCA14085 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: FASN Full Name: fatty acid synthase Category: mRNA Synonyms: FAS|OA-519|SDR27X1 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 82078333 End Site(bp): 82098332 Gene Summary: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000169710 HGNC ID: HGNC:3594 Entrez Gene: 2194

Expression Profile of FASN Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-424-5p YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-541-3p YES NO NO hsa-miR-654-5p YES NO NO Display: