| ncRNA Symbol: | OSTM1 |
| Full Name: | osteoclastogenesis associated transmembrane protein 1 |
| Category: | mRNA |
| Synonyms: | GIPN|GL|HSPC019|OPTB5 |
| Chromosome: | chr6 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 108041409 | End Site(bp): | 108165854 | |
| Gene Summary: | This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq, Jul 2008] |
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