Entry Detail



General Information

Database ID:BRCA14606
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:STS
Full Name:steroid sulfatase
Category:mRNA
Synonyms:ARSC|ARSC1|ASC|ES|SSDD|XLI
Chromosome:chrX
Strand:+
Coordinate:
Start Site(bp):7219456End Site(bp):7354810
Gene Summary:This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene (PMID:17601726). [provided by RefSeq, Mar 2016]
External Links:
Ensembl ID:ENSG00000101846
HGNC ID:HGNC:11425
Entrez Gene:412



Expression Profile of STS Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
NO
hsa-miR-107
YES
YES
NO
hsa-miR-139-5p
YES
YES
NO
hsa-miR-147a
YES
NO
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-190a-5p
YES
YES
NO
hsa-miR-190b
YES
YES
NO
hsa-miR-19a-3p
YES
YES
NO
hsa-miR-19b-3p
YES
YES
NO
hsa-miR-205-5p
YES
YES
YES
hsa-miR-25-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-32-5p
YES
YES
NO
hsa-miR-33a-5p
YES
YES
YES
hsa-miR-33b-5p
YES
YES
YES
hsa-miR-363-3p
YES
YES
NO
hsa-miR-367-3p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-92a-3p
YES
YES
NO
hsa-miR-92b-3p
YES
YES
NO
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