ctcRbase

Entry Detail

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General Information

Database ID: BRCA14644 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: LTBP1 Full Name: latent transforming growth factor beta binding protein 1 Category: mRNA Synonyms: - Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 32946972 End Site(bp): 33399509 Gene Summary: The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000049323 HGNC ID: HGNC:6714 Entrez Gene: 4052

Expression Profile of LTBP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES YES hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-141-3p YES YES NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-191-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-369-3p YES NO NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-379-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-590-5p YES YES NO Display: