ctcRbase

Entry Detail

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General Information

Database ID: BRCA14842 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: ATP6V1C1 Full Name: ATPase H+ transporting V1 subunit C1 Category: mRNA Synonyms: ATP6C|ATP6D|VATC|Vma5 Chromosome: chr8 Strand: + Coordinate: Start Site(bp): 103021063 End Site(bp): 103073051 Gene Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000155097 HGNC ID: HGNC:856 Entrez Gene: 528

Expression Profile of ATP6V1C1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-1323 YES NO NO hsa-miR-144-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-149-5p YES YES NO hsa-miR-155-5p YES NO YES hsa-miR-186-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-219a-5p YES NO YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-422a YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-495-3p YES NO NO hsa-miR-496 YES YES NO hsa-miR-548o-3p YES NO NO hsa-miR-98-5p YES YES NO Display: