ctcRbase

Entry Detail

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General Information

Database ID: BRCA14866 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: MAP3K20 Full Name: mitogen-activated protein kinase kinase kinase 20 Category: mRNA Synonyms: AZK|CNM6|MLK7|MLT|MLTK|MLTKalpha|MLTKbeta|MRK|SFMMP|ZAK|mlklak|pk Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 173075435 End Site(bp): 173268010 Gene Summary: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000091436 HGNC ID: HGNC:17797 Entrez Gene: 51776

Expression Profile of MAP3K20 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-1271-5p YES NO YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-137 YES NO YES hsa-miR-140-3p YES NO YES hsa-miR-142-3p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-17-5p YES YES NO hsa-miR-182-5p YES NO YES hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-18a-5p YES NO YES hsa-miR-18b-5p YES NO YES hsa-miR-195-5p YES NO YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-23a-3p YES NO YES hsa-miR-23b-3p YES NO YES hsa-miR-25-3p YES NO YES hsa-miR-300 YES YES YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-32-5p YES NO YES hsa-miR-328-3p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-342-3p YES YES YES hsa-miR-363-3p YES NO YES hsa-miR-367-3p YES NO YES hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-424-5p YES NO YES hsa-miR-425-5p YES YES YES hsa-miR-429 YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-491-5p YES YES NO hsa-miR-497-5p YES NO YES hsa-miR-519d-3p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-520f-3p YES NO YES hsa-miR-543 YES NO YES hsa-miR-876-5p YES YES YES hsa-miR-92a-3p YES NO YES hsa-miR-92b-3p YES NO YES hsa-miR-93-5p YES YES NO hsa-miR-96-5p YES NO YES Display: