ctcRbase

Entry Detail

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General Information

Database ID: BRCA15136 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: FBXW11 Full Name: F-box and WD repeat domain containing 11 Category: mRNA Synonyms: BTRC2|BTRCP2|FBW1B|FBXW1B|Fbw11|Hos Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 171861549 End Site(bp): 172006873 Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000072803 HGNC ID: HGNC:13607 Entrez Gene: 23291

Expression Profile of FBXW11 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-141-3p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-150-5p YES YES YES hsa-miR-152-3p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p YES NO YES hsa-miR-186-5p YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199a-5p YES YES NO hsa-miR-199b-3p YES NO YES hsa-miR-199b-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200a-3p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-211-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-217 YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-429 YES YES YES hsa-miR-448 YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-520f-3p YES NO YES hsa-miR-543 YES YES NO hsa-miR-93-5p YES YES YES hsa-miR-96-5p YES YES YES Display: