ctcRbase

Entry Detail

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General Information

Database ID: BRCA15189 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: NOS1AP Full Name: nitric oxide synthase 1 adaptor protein Category: mRNA Synonyms: 6330408P19Rik|CAPON Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 162069774 End Site(bp): 162370475 Gene Summary: This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2009] External Links: Ensembl ID: ENSG00000198929 HGNC ID: HGNC:16859 Entrez Gene: 9722

Expression Profile of NOS1AP Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-330-5p YES YES NO hsa-miR-34a-5p NO YES YES hsa-miR-34c-5p NO YES YES hsa-miR-449a NO YES YES hsa-miR-449b-5p NO YES YES hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES NO Display: