ctcRbase

Entry Detail

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General Information

Database ID: BRCA15311 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HSD3B7 Full Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 Category: mRNA Synonyms: CBAS1|PFIC4|SDR11E3 Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 30985207 End Site(bp): 30989152 Gene Summary: This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] External Links: Ensembl ID: ENSG00000099377 HGNC ID: HGNC:18324 Entrez Gene: 80270

Expression Profile of HSD3B7 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-542-3p YES YES NO Display: