ctcRbase

Entry Detail

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General Information

Database ID: BRCA15380 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: H2AFY2 Full Name: H2A histone family member Y2 Category: mRNA Synonyms: macroH2A2 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 70052796 End Site(bp): 70112280 Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and may participate in stable X chromosome inactivation. [provided by RefSeq, Oct 2015] External Links: Ensembl ID: ENSG00000099284 HGNC ID: HGNC:14453 Entrez Gene: 55506

Expression Profile of H2AFY2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-599 YES YES NO hsa-miR-876-5p YES YES NO Display: