ctcRbase

Entry Detail

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General Information

Database ID: BRCA15519 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PLEK2 Full Name: pleckstrin 2 Category: mRNA Synonyms: - Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 67386983 End Site(bp): 67412200 Gene Summary: The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015] External Links: Ensembl ID: ENSG00000100558 HGNC ID: HGNC:19238 Entrez Gene: 26499

Expression Profile of PLEK2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-9-5p YES YES NO Display: