ctcRbase

Entry Detail

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General Information

Database ID: BRCA15807 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PRLR Full Name: prolactin receptor Category: mRNA Synonyms: HPRL|MFAB|RI-PRLR|hPRLrI Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 35048756 End Site(bp): 35230589 Gene Summary: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011] External Links: Ensembl ID: ENSG00000113494 HGNC ID: HGNC:9446 Entrez Gene: 5618

Expression Profile of PRLR Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES NO YES hsa-miR-142-3p YES NO YES hsa-miR-218-5p YES NO YES hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-506-3p YES NO YES hsa-miR-625-5p YES NO NO Display: