ctcRbase

Entry Detail

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General Information

Database ID: BRCA15961 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SSH3 Full Name: slingshot protein phosphatase 3 Category: mRNA Synonyms: SSH3L Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 67303448 End Site(bp): 67312607 Gene Summary: The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM, Mar 2008] External Links: Ensembl ID: ENSG00000172830 HGNC ID: HGNC:30581 Entrez Gene: 54961

Expression Profile of SSH3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-2-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-206 YES YES NO hsa-miR-485-5p YES YES YES hsa-miR-542-3p YES YES NO hsa-miR-613 YES YES NO hsa-miR-874-3p YES YES YES Display: