Entry Detail



General Information

Database ID:BRCA15981
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:WDR5
Full Name:WD repeat domain 5
Category:mRNA
Synonyms:BIG-3|CFAP89|SWD3
Chromosome:chr9
Strand:+
Coordinate:
Start Site(bp):134135365End Site(bp):134159968
Gene Summary:This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000196363
HGNC ID:HGNC:12757
Entrez Gene:11091



Expression Profile of WDR5 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-10a-5p
YES
YES
NO
hsa-miR-10b-5p
YES
YES
NO
hsa-miR-150-5p
YES
YES
NO
hsa-miR-182-5p
YES
YES
YES
hsa-miR-186-5p
YES
YES
NO
hsa-miR-31-5p
YES
YES
YES
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