ctcRbase

Entry Detail

---



General Information

Database ID: BRCA16132 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: THRB Full Name: thyroid hormone receptor beta Category: mRNA Synonyms: C-ERBA-2|C-ERBA-BETA|ERBA2|GRTH|NR1A2|PRTH|THR1|THRB1|THRB2 Chromosome: chr3 Strand: - Coordinate: Start Site(bp): 24117160 End Site(bp): 24495282 Gene Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000151090 HGNC ID: HGNC:11799 Entrez Gene: 7068

Expression Profile of THRB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-103a-3p YES NO YES hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-107 YES NO YES hsa-miR-128-3p YES NO YES hsa-miR-137 YES NO YES hsa-miR-138-5p YES NO YES hsa-miR-1-3p YES NO YES hsa-miR-143-3p YES NO YES hsa-miR-17-5p YES NO YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-19a-3p YES NO YES hsa-miR-19b-3p YES NO YES hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-206 YES NO YES hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-21-5p YES YES YES hsa-miR-218-5p YES NO YES hsa-miR-219a-5p YES NO YES hsa-miR-23a-3p YES NO YES hsa-miR-23b-3p YES NO YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-300 YES NO YES hsa-miR-329-3p YES NO YES hsa-miR-362-3p YES NO YES hsa-miR-381-3p YES NO YES hsa-miR-425-5p YES NO YES hsa-miR-429 YES NO YES hsa-miR-431-5p YES NO YES hsa-miR-495-3p YES YES YES hsa-miR-496 YES YES YES hsa-miR-519d-3p YES NO YES hsa-miR-520f-3p YES NO YES hsa-miR-590-5p YES YES YES hsa-miR-613 YES NO YES hsa-miR-874-3p YES YES YES hsa-miR-93-5p YES NO YES Display: