ctcRbase

Entry Detail

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General Information

Database ID: BRCA16134 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: ZIC2 Full Name: Zic family member 2 Category: mRNA Synonyms: HPE5 Chromosome: chr13 Strand: + Coordinate: Start Site(bp): 99981772 End Site(bp): 99986773 Gene Summary: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2016] External Links: Ensembl ID: ENSG00000043355 HGNC ID: HGNC:12873 Entrez Gene: 7546

Expression Profile of ZIC2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p YES NO YES hsa-miR-205-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-543 YES YES YES hsa-miR-873-5p YES YES NO hsa-miR-96-5p YES YES YES Display: