ctcRbase

Entry Detail

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General Information

Database ID: BRCA16553 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SF3A2 Full Name: splicing factor 3a subunit 2 Category: mRNA Synonyms: PRP11|PRPF11|SAP62|SF3a66 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 2236504 End Site(bp): 2248679 Gene Summary: This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000104897 HGNC ID: HGNC:10766 Entrez Gene: 8175

Expression Profile of SF3A2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-485-5p YES YES NO Display: