ctcRbase

Entry Detail

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General Information

Database ID: BRCA16828 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ELOA Full Name: elongin A Category: mRNA Synonyms: SIII|SIII p110|TCEB3|TCEB3A Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 23743155 End Site(bp): 23762059 Gene Summary: This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000011007 HGNC ID: HGNC:11620 Entrez Gene: 6924

Expression Profile of ELOA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p NO YES YES hsa-miR-106b-5p NO YES YES hsa-miR-142-3p NO YES YES hsa-miR-17-5p NO YES YES hsa-miR-192-5p YES NO YES hsa-miR-19a-3p NO YES YES hsa-miR-19b-3p NO YES YES hsa-miR-20a-5p NO YES YES hsa-miR-20b-5p NO YES YES hsa-miR-215-5p YES NO YES hsa-miR-23a-3p YES NO YES hsa-miR-23b-3p YES NO YES hsa-miR-25-3p NO YES YES hsa-miR-302a-3p NO YES YES hsa-miR-302b-3p NO YES YES hsa-miR-302c-3p NO YES YES hsa-miR-302d-3p NO YES YES hsa-miR-302e NO YES YES hsa-miR-32-5p NO YES YES hsa-miR-363-3p NO YES YES hsa-miR-367-3p NO YES YES hsa-miR-372-3p NO YES YES hsa-miR-373-3p NO YES YES hsa-miR-376c-3p NO YES YES hsa-miR-410-3p NO YES YES hsa-miR-519d-3p NO YES YES hsa-miR-520a-3p NO YES YES hsa-miR-520b NO YES YES hsa-miR-520c-3p NO YES YES hsa-miR-520d-3p NO YES YES hsa-miR-520e NO YES YES hsa-miR-92a-3p NO YES YES hsa-miR-92b-3p NO YES YES hsa-miR-93-5p NO YES YES Display: