ctcRbase

Entry Detail

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General Information

Database ID: BRCA17346 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SRC Full Name: SRC proto-oncogene, non-receptor tyrosine kinase Category: mRNA Synonyms: ASV|SRC1|THC6|c-SRC|p60-Src Chromosome: chr20 Strand: + Coordinate: Start Site(bp): 37344685 End Site(bp): 37406050 Gene Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000197122 HGNC ID: HGNC:11283 Entrez Gene: 6714

Expression Profile of SRC Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-137 YES YES YES hsa-miR-1-3p YES YES NO hsa-miR-141-3p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-149-5p YES NO YES hsa-miR-153-3p YES YES YES hsa-miR-184 YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-206 YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-485-5p YES NO YES hsa-miR-488-3p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-599 YES YES NO hsa-miR-613 YES YES NO Display: