Entry Detail



General Information

Database ID:BRCA17395
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:MOGS
Full Name:mannosyl-oligosaccharide glucosidase
Category:mRNA
Synonyms:CDG2B|CWH41|DER7|GCS1
Chromosome:chr2
Strand:-
Coordinate:
Start Site(bp):74461057End Site(bp):74465410
Gene Summary:This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
External Links:
Ensembl ID:ENSG00000115275
HGNC ID:HGNC:24862
Entrez Gene:7841



Expression Profile of MOGS Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-143-3p
YES
YES
YES
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
YES
hsa-miR-23b-3p
YES
YES
YES
hsa-miR-299-3p
YES
YES
NO
hsa-miR-326
YES
YES
NO
hsa-miR-330-5p
YES
YES
NO
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