| ncRNA Symbol: | ST6GALNAC1 | | Full Name: | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 | | Category: | mRNA | | Synonyms: | HSY11339|SIAT7A|ST6GalNAcI|STYI | | Chromosome: | chr17 | | Strand: | - | | Coordinate: | | Start Site(bp): | 76624761 | End Site(bp): | 76643838 |
| | Gene Summary: | Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM, Mar 2008] | | External Links: | |
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