ctcRbase

Entry Detail

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General Information

Database ID: BRCA17651 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: MXD1 Full Name: MAX dimerization protein 1 Category: mRNA Synonyms: BHLHC58|MAD|MAD1 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 69897688 End Site(bp): 69942945 Gene Summary: This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011] External Links: Ensembl ID: ENSG00000059728 HGNC ID: HGNC:6761 Entrez Gene: 4084

Expression Profile of MXD1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-101-3p YES YES YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-129-2-3p YES NO YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-137 YES YES YES hsa-miR-138-5p YES NO YES hsa-miR-1-3p YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-149-5p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-205-5p YES NO YES hsa-miR-206 YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-21-5p YES NO YES hsa-miR-221-3p YES NO YES hsa-miR-222-3p YES NO YES hsa-miR-22-3p YES YES YES hsa-miR-25-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-300 YES YES YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-335-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-376c-3p YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-382-5p YES YES YES hsa-miR-410-3p YES YES YES hsa-miR-452-5p YES NO YES hsa-miR-454-3p YES YES YES hsa-miR-485-5p YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES NO NO hsa-miR-506-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-590-5p YES NO YES hsa-miR-599 YES YES NO hsa-miR-613 YES YES YES hsa-miR-625-5p YES NO NO hsa-miR-758-3p YES YES YES hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-93-5p YES YES YES hsa-miR-9-5p YES YES NO hsa-miR-98-5p YES YES YES Display: