ctcRbase

Entry Detail

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General Information

Database ID: BRCA17861 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: STX1A Full Name: syntaxin 1A Category: mRNA Synonyms: HPC-1|P35-1|STX1|SYN1A Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 73699206 End Site(bp): 73719672 Gene Summary: This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] External Links: Ensembl ID: ENSG00000106089 HGNC ID: HGNC:11433 Entrez Gene: 6804

Expression Profile of STX1A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-217 YES YES YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-429 YES NO YES hsa-miR-491-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-9-5p YES YES YES Display: