ctcRbase

Entry Detail

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General Information

Database ID: BRCA18030 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: CHMP4C Full Name: charged multivesicular body protein 4C Category: mRNA Synonyms: SNF7-3|Shax3|VPS32C Chromosome: chr8 Strand: + Coordinate: Start Site(bp): 81732434 End Site(bp): 81759515 Gene Summary: CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008] External Links: Ensembl ID: ENSG00000164695 HGNC ID: HGNC:30599 Entrez Gene: 92421

Expression Profile of CHMP4C Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-122-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-324-5p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-520f-3p YES NO YES hsa-miR-665 YES NO YES Display: