ctcRbase

Entry Detail

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General Information

Database ID: BRCA18063 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: RGS17 Full Name: regulator of G protein signaling 17 Category: mRNA Synonyms: RGS-17|RGSZ2|hRGS17 Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 153004459 End Site(bp): 153131249 Gene Summary: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000091844 HGNC ID: HGNC:14088 Entrez Gene: 26575

Expression Profile of RGS17 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES NO YES hsa-miR-182-5p YES YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-499a-5p YES YES NO hsa-miR-599 YES YES NO hsa-miR-873-5p YES YES YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-96-5p YES YES YES Display: