ctcRbase

Entry Detail

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General Information

Database ID: BRCA18515 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: TGIF2 Full Name: TGFB induced factor homeobox 2 Category: mRNA Synonyms: - Chromosome: chr20 Strand: + Coordinate: Start Site(bp): 36573488 End Site(bp): 36593950 Gene Summary: The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010] External Links: Ensembl ID: ENSG00000118707 HGNC ID: HGNC:15764 Entrez Gene: 60436

Expression Profile of TGIF2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-103a-3p YES NO YES hsa-miR-107 YES NO YES hsa-miR-128-3p YES NO YES hsa-miR-129-5p YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-140-3p YES NO YES hsa-miR-141-3p YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-148a-3p YES NO YES hsa-miR-148b-3p YES NO YES hsa-miR-152-3p YES NO YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-191-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-200a-3p YES YES NO hsa-miR-206 YES YES YES hsa-miR-218-5p YES YES YES hsa-miR-24-3p YES NO YES hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-340-5p YES YES YES hsa-miR-346 YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-424-5p YES YES YES hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES NO NO hsa-miR-543 YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-613 YES YES YES hsa-miR-653-5p YES YES NO Display: