ctcRbase

Entry Detail

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General Information

Database ID: BRCA18785 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: ARHGEF26 Full Name: Rho guanine nucleotide exchange factor 26 Category: mRNA Synonyms: CSGEF|HMFN1864|SGEF Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 154121003 End Site(bp): 154257827 Gene Summary: This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] External Links: Ensembl ID: ENSG00000114790 HGNC ID: HGNC:24490 Entrez Gene: 26084

Expression Profile of ARHGEF26 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-1297 YES NO YES hsa-miR-130a-3p NO YES YES hsa-miR-130b-3p NO YES YES hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-22-3p NO YES YES hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-27a-3p NO YES YES hsa-miR-27b-3p NO YES YES hsa-miR-300 YES YES NO hsa-miR-301a-3p NO YES YES hsa-miR-301b-3p NO YES YES hsa-miR-339-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-454-3p NO YES YES hsa-miR-490-3p YES YES NO hsa-miR-491-5p YES YES NO Display: