ctcRbase

Entry Detail

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General Information

Database ID: BRCA18795 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HDAC7 Full Name: histone deacetylase 7 Category: mRNA Synonyms: HD7|HD7A|HDAC7A Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 47782722 End Site(bp): 47833132 Gene Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000061273 HGNC ID: HGNC:14067 Entrez Gene: 51564

Expression Profile of HDAC7 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-140-5p YES YES YES hsa-miR-143-3p YES YES YES hsa-miR-182-5p YES NO YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-299-3p YES YES YES hsa-miR-329-3p YES NO NO hsa-miR-342-3p YES YES NO hsa-miR-375 YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-532-3p YES NO YES hsa-miR-543 YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-96-5p YES YES YES Display: