| ncRNA Symbol: | TRPC6 |
| Full Name: | transient receptor potential cation channel subfamily C member 6 |
| Category: | mRNA |
| Synonyms: | FSGS2|TRP6 |
| Chromosome: | chr11 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 101451564 | End Site(bp): | 101872562 |
|
| Gene Summary: | The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009] |
| External Links: | |