Entry Detail



General Information

Database ID:BRCA19500
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:PAK3
Full Name:p21 (RAC1) activated kinase 3
Category:mRNA
Synonyms:ARA|MRX30|MRX47|OPHN3|PAK-3|PAK3beta|bPAK|beta-PAK
Chromosome:chrX
Strand:+
Coordinate:
Start Site(bp):110944285End Site(bp):111227361
Gene Summary:The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2017]
External Links:
Ensembl ID:ENSG00000077264
HGNC ID:HGNC:8592
Entrez Gene:5063



Expression Profile of PAK3 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A