Entry Detail



General Information

Database ID:BRCA20431
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:MAPT
Full Name:microtubule associated protein tau
Category:mRNA
Synonyms:DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU
Chromosome:chr17
Strand:+
Coordinate:
Start Site(bp):45894382End Site(bp):46028334
Gene Summary:This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000186868
HGNC ID:HGNC:6893
Entrez Gene:4137



Expression Profile of MAPT Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-132-3p
YES
YES
YES
hsa-miR-181a-5p
YES
YES
YES
hsa-miR-181b-5p
YES
YES
YES
hsa-miR-181c-5p
YES
YES
YES
hsa-miR-181d-5p
YES
YES
YES
hsa-miR-197-3p
YES
YES
NO
hsa-miR-212-3p
YES
YES
YES
hsa-miR-27a-3p
YES
NO
YES
hsa-miR-27b-3p
YES
NO
YES
hsa-miR-34a-5p
YES
YES
YES
hsa-miR-34c-5p
YES
YES
YES
hsa-miR-423-5p
YES
NO
NO
hsa-miR-449a
YES
YES
YES
hsa-miR-449b-5p
YES
YES
YES
hsa-miR-625-5p
YES
NO
NO
hsa-miR-668-3p
YES
NO
YES
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