ctcRbase

Entry Detail

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General Information

Database ID: BRCA21079 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: CEBPA Full Name: CCAAT enhancer binding protein alpha Category: mRNA Synonyms: C/EBP-alpha|CEBP Chromosome: chr19 Strand: - Coordinate: Start Site(bp): 33299934 End Site(bp): 33302564 Gene Summary: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013] External Links: Ensembl ID: ENSG00000245848 HGNC ID: HGNC:1833 Entrez Gene: 1050

Expression Profile of CEBPA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-1323 YES NO NO hsa-miR-144-3p YES NO YES hsa-miR-154-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-190a-5p NO YES YES hsa-miR-190b NO YES YES hsa-miR-205-5p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-31-5p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-326 YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-374a-5p NO YES YES hsa-miR-374b-5p NO YES YES hsa-miR-381-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-548o-3p YES NO NO hsa-miR-615-3p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: