ctcRbase

Entry Detail

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General Information

Database ID: BRCA21334 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PPP6R2 Full Name: protein phosphatase 6 regulatory subunit 2 Category: mRNA Synonyms: KIAA0685|PP6R2|SAP190|SAPS2 Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 50343304 End Site(bp): 50445090 Gene Summary: The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment. [provided by RefSeq, May 2017] External Links: Ensembl ID: ENSG00000100239 HGNC ID: HGNC:19253 Entrez Gene: 9701

Expression Profile of PPP6R2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-107 YES YES YES hsa-miR-124-3p YES NO YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-137 YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-25-3p YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-32-5p YES YES NO hsa-miR-339-5p YES YES YES hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-874-3p YES YES YES hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-93-5p YES YES YES Display: