ctcRbase

Entry Detail

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General Information

Database ID: BRCA21612 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: TBL1X Full Name: transducin beta like 1 X-linked Category: mRNA Synonyms: EBI|SMAP55|TBL1 Chromosome: chrX Strand: + Coordinate: Start Site(bp): 9463295 End Site(bp): 9719743 Gene Summary: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq, Nov 2008] External Links: Ensembl ID: ENSG00000101849 HGNC ID: HGNC:11585 Entrez Gene: 6907

Expression Profile of TBL1X Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-10a-5p YES NO YES hsa-miR-10b-5p YES NO YES hsa-miR-1271-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-138-5p YES NO YES hsa-miR-139-5p YES YES NO hsa-miR-142-3p YES YES YES hsa-miR-143-3p YES YES NO hsa-miR-149-5p YES NO YES hsa-miR-17-5p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p YES NO YES hsa-miR-185-5p YES NO NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-214-3p YES NO NO hsa-miR-219a-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-486-5p YES NO YES hsa-miR-494-3p YES NO YES hsa-miR-519d-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-625-5p YES NO NO hsa-miR-93-5p YES YES YES hsa-miR-96-5p YES YES YES Display: