Entry Detail



General Information

Database ID:BRCA22178
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:ACVR1C
Full Name:activin A receptor type 1C
Category:mRNA
Synonyms:ACVRLK7|ALK7
Chromosome:chr2
Strand:-
Coordinate:
Start Site(bp):157526767End Site(bp):157629005
Gene Summary:ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
External Links:
Ensembl ID:ENSG00000123612
HGNC ID:HGNC:18123
Entrez Gene:130399



Expression Profile of ACVR1C Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
YES
hsa-let-7b-5p
YES
YES
YES
hsa-let-7c-5p
YES
YES
YES
hsa-let-7d-5p
YES
YES
YES
hsa-let-7e-5p
YES
YES
YES
hsa-let-7f-5p
YES
YES
YES
hsa-let-7g-5p
YES
YES
YES
hsa-let-7i-5p
YES
YES
YES
hsa-miR-1297
YES
YES
YES
hsa-miR-200b-3p
YES
YES
YES
hsa-miR-200c-3p
YES
YES
YES
hsa-miR-23a-3p
YES
NO
YES
hsa-miR-23b-3p
YES
NO
YES
hsa-miR-26a-5p
YES
YES
YES
hsa-miR-26b-5p
YES
YES
YES
hsa-miR-27a-3p
NO
YES
YES
hsa-miR-27b-3p
NO
YES
YES
hsa-miR-429
YES
YES
YES
hsa-miR-98-5p
YES
YES
YES
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