| ncRNA Symbol: | BCL3 | | Full Name: | BCL3, transcription coactivator | | Category: | mRNA | | Synonyms: | BCL4|D19S37 | | Chromosome: | chr19 | | Strand: | + | | Coordinate: | | Start Site(bp): | 44747705 | End Site(bp): | 44760044 | | | Gene Summary: | This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008] | | External Links: | |
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