ctcRbase

Entry Detail

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General Information

Database ID: BRCA22390 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: IRX5 Full Name: iroquois homeobox 5 Category: mRNA Synonyms: HMMS|IRX-2a|IRXB2 Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 54930862 End Site(bp): 54934485 Gene Summary: This gene encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation, and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] External Links: Ensembl ID: ENSG00000176842 HGNC ID: HGNC:14361 Entrez Gene: 10265

Expression Profile of IRX5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-208a-3p YES YES YES hsa-miR-208b-3p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-486-5p YES YES YES hsa-miR-490-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-499a-5p YES YES YES hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-655-3p YES NO YES Display: