Entry Detail



General Information

Database ID:BRCA22660
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:HS3ST3A1
Full Name:heparan sulfate-glucosamine 3-sulfotransferase 3A1
Category:mRNA
Synonyms:3-OST-3A|3OST3A1
Chromosome:chr17
Strand:-
Coordinate:
Start Site(bp):13495689End Site(bp):13601927
Gene Summary:Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta. [provided by RefSeq, Dec 2014]
External Links:
Ensembl ID:ENSG00000153976
HGNC ID:HGNC:5196
Entrez Gene:9955



Expression Profile of HS3ST3A1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-181a-5p
YES
YES
YES
hsa-miR-181b-5p
YES
YES
YES
hsa-miR-181c-5p
YES
YES
YES
hsa-miR-181d-5p
YES
YES
YES
hsa-miR-200b-3p
YES
YES
YES
hsa-miR-200c-3p
YES
YES
YES
hsa-miR-216b-5p
YES
YES
NO
hsa-miR-429
YES
YES
YES
hsa-miR-494-3p
YES
YES
NO
hsa-miR-543
YES
YES
YES
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