ctcRbase

Entry Detail

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General Information

Database ID: BRCA22802 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: KCNMB4 Full Name: potassium calcium-activated channel subfamily M regulatory beta subunit 4 Category: mRNA Synonyms: - Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 70366276 End Site(bp): 70434292 Gene Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000135643 HGNC ID: HGNC:6289 Entrez Gene: 27345

Expression Profile of KCNMB4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-186-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-488-3p YES YES NO Display: