ctcRbase

Entry Detail

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General Information

Database ID: BRCA23538 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: BMP4 Full Name: bone morphogenetic protein 4 Category: mRNA Synonyms: BMP2B|BMP2B1|MCOPS6|OFC11|ZYME Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 53949736 End Site(bp): 53958761 Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016] External Links: Ensembl ID: ENSG00000125378 HGNC ID: HGNC:1071 Entrez Gene: 652

Expression Profile of BMP4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-142-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-876-5p YES YES NO Display: